PRELAXAN - A HIGHLY EFFECTIVE REMEDY FOR COMBATING CHRONIC CONSTIPATION

Prelaksan (lactulose) is a highly effective drug produced by Felitsata Ukraine, which has a long-lasting therapeutic effect and is intended for the treatment of patients with hepatitis, hepatic encephalopathy, hepatic failure, hepatic precoma and coma, cirrhosis of the liver with a tendency to hyperammonemia, salmonellosis (carriers of salmonella), intestinal dysbacteriosis, chronic constipation, hypercholesterolemia, intoxication of various etiologies.

The drug is well tolerated.

It is known that lactulose was first obtained in 1929 from dairy products. As a synthetic disaccharide, lactulose is not absorbed after oral administration and enters the large intestine practically unchanged, which explains its good tolerability. Prelaksan belongs to the group of oligosaccharide agents, which in terms of their metabolic effects are similar to the so-called dietary fibers, although they do not have the high-molecular structure characteristic of them.

Currently, Prelaksan is successfully used to treat children and adults who are chronic carriers of salmonella, as it helps restore normal intestinal microbiocenosis and eliminate the pathogen.

Prelaksan is widely used as a laxative, including in patients with chronic constipation requiring long-term therapy (especially in elderly and debilitated patients). Prelaksan is the agent of choice if there is a need to use effective and safe agents that are well tolerated, since it is devoid of side effects and its effectiveness does not decrease with prolonged use.

In the large intestine, under the influence of intestinal microflora, lactulose is transformed into low-molecular organic acids (lactic, acetic). As a result, the pH decreases and osmotic changes occur, which stimulate peristalsis of the large intestine and normalize the consistency of feces, contributing to physiological defecation and the elimination of constipation.

The results of studies conducted in recent years indicate that Prelaksan is effective in hyperlipidemia and cholelithiasis: it reduces the concentration of cholesterol, triglycerides and low-density lipoproteins in the blood serum, promotes the lysis of cholesterol stones in the biliary tract. The action of lactulose is due to its ability to influence the metabolism of bile acids and cholesterol in the liver, and reduce the lithogenic properties of bile.

Prelaksan also reduces the level of ammonia and other nitrogenous wastes in the blood by inhibiting the proteolytic flora of the large intestine, binds ammonia and removes it from the body with feces, which makes the drug suitable for the treatment of patients with liver failure and hepatic encephalopathy.

Currently, Prelaksan is used in the treatment of patients with type II diabetes mellitus and patients with renal failure.

Prelaksan is recommended for adults to take 2 tablespoons once a day. For prolonged chronic constipation, the dose can be increased to 4 tablespoons per day. Children from 5 years old - 1-2 teaspoons once a day. Children from 1 year old - 0.5-1 teaspoon once a day. For the prevention of constipation, the duration of treatment is 14-21 days.

The proven effectiveness and good tolerability of Prelaksan allow us to recommend it for the treatment of constipation in patients with various pathologies.