PRALAXAN AND ITS INFLUENCE ON THE INTESTINAL MICROFLORA

When taking Prelaksan, a decrease in allergic manifestations was noted in children who took Prelaksan, without additional antihistamines.

When taking kefir with lactulose, it was noted that it has a positive effect on intestinal function, eliminates constipation and other intestinal disorders in children.

The use of kefir with lactulose improves the clinical picture: reduces the manifestations of atopic dermatitis, improves appetite, improves the condition after an intestinal infection, improves the general condition of the body and intestinal function after antibiotic therapy" - the results of studies of kefir with the introduction of lactulose.

Causes of skin diseases

In 77-85% of patients with atopic dermatitis, urticaria and other skin diseases, dysbacteriosis of the large intestine is detected, i.e. a reduction in bifido- and lactobacteria and an increase in pathogenic microorganisms.

At the same time, in the human body:

• the synthesis of substances necessary for the further formation of immunoglobulins and nonspecific factors of the body's defense is reduced;

• the synthesis of vitamins, hydrogen, methane, carbon dioxide, alcohol, lactic acid, biologically active substances (volatile fatty acids, hormones, natural antibiotics) is reduced;

• the synthesis of toxins increases: ammonia, hydrogen sulfide, mercaptans, disulfides, indole, skatole, mycotoxins, etc.) and harmful enzymes (b-glucuronidase, nitroreductase, azoreductase),

• the permeability of the intestinal wall, which is normally provided by bifido- and lactobacteria, is disrupted, resulting in the translocation (penetration) of toxins into the systemic bloodstream.

When poisons and toxins enter the bloodstream, the liver and kidneys begin to work with redoubled force.

All of the above factors negatively affect the human immune system and, accordingly, are reflected in the condition of the skin.

Next - dermatitis, diathesis, psoriasis

Treatment and prevention strategy

To get rid of many skin diseases and further maintain the skin in a healthy state, it is necessary to get rid of colon dysbiosis, that is, to increase the population of protective normoflora, which will result in:

• reduction in the concentration of toxic substances in the bloodstream,

• increased concentration in the systemic bloodstream of biologically active substances that have a beneficial effect on the condition of the skin,

• activation of the immune system.

Thus, it is necessary, first of all, to give the protective intestinal microflora (bifido- and lactobacteria) advantages over pathogenic bacteria, that is, to provide beneficial microflora with the energy necessary for its growth and vital activity.

Lactulose (the active ingredient of Prelaksan), has been known to doctors for over 40 years. In no study, during the entire period of use of lactulose, was there any direct or indirect evidence of its mutagenic, genotoxic or teratogenic effects.

Lactulose does not penetrate the bloodstream and does not have a systemic effect on the body. It is safe for pregnant women and newborns. Being a sugar, lactulose does not increase the blood glucose content and may be indicated for diabetes.